2 edition of Transport mechanisms in epithelia found in the catalog.
Transport mechanisms in epithelia
Alfred Benzon Symposium (5th 1972 Royal Danish Academy of Sciences and Letters)
|Statement||edited by H.H. Ussing [and] N.A. Thorn.|
|Contributions||Ussing, H. H., Thorn, Niels Anker., Alfred Benzon Foundation.|
1. (Na+ - K+)- ATPase generates electrochemical potential difference for Na+ across BL membrane 2. Na+ moves passively across BB membrane, and also drives uptake of K+ and Cl-from lumen 3. K+ channels at both membranes allow recirculation of K+ and control Δ. 4. Trans-epithelial Na+ transport sets up trans-epithelial Δ, which drives paracellular Cl-transport into cleft. Purchase Molecular Mechanisms of Water Transport Across Biological Membranes, Volume - 1st Edition. Print Book & E-Book. ISBN ,
Back to TI1 Learning Objectives Describes the basic characteristics of an epithelial cell List 4 examples of epithelial tissues Briefly describe primary active transport and passive transport Outline a method for measuring trans-epithelial transport in a whole organ and in isolated epithelium Explain how to identify transport processes which occur at either side of the. The membrane transport mechanisms described in this section move materials through the cytoplasm of the epithelial cells, a process termed transcellular transport. However, diffusion and osmosis may also occur to a limited extent in the very tiny spaces between epithelial cells, a process termed paracellu-lar transport.
Three epithelia are examined as a means of exploring molecular mechanisms of fluid and ion transport. The Malpighian tubules of insects are the site of urine production and can transport a variety of ions and organic compounds. The energy for these processes is generated by a hydrogen ATPase at the apical membrane while a Na+/K+ ATPase energizes the basal surface. TY - CHAP. T1 - Membrane Transport of Folates. AU - Matherly, Larry H. AU - Goldman, I. David. PY - /12/1. Y1 - /12/1. N2 - The chapter reviews the current understanding of the transport mechanisms for folates in mammalian cells-their molecular identities and organization, tissue expression, regulation, structures, and their kinetic and thermodynamic by:
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With few exceptions, all the internal and external body surfaces of animals, such as the skin, stomach, and intestines, are covered with a layer of epithelial cells called an epithelium (see Figure ). Many epithelial cells transport ions or small molecules from one side to the other of the epithelium.
Those lining the stomach, for instance, secrete hydrochloric acid into the stomach lumen Cited by: 2. Mechanisms of Membrane Transport of Folates into Cells and Across Epithelia Article Literature Review (PDF Available) in Annual Review of Nutrition 31(1) August with Reads.
Mechanisms of membrane transport of folates into cells and across epithelia. Zhao R(1), Diop-Bove N, Visentin M, Goldman ID. Author information: (1)Departments of Medicine and Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NYby: Transport mechanisms in epithelia.
Copenhagen, Munksgaard; New York, Academic Press [©] (OCoLC) Online version: Alfred Benzon Symposium (5th: Copenhagen, Denmark). Transport mechanisms in epithelia. Copenhagen, Munksgaard; New York, Academic Press [©] (OCoLC) Material Type: Conference publication: Document. Epithelial Transport Physiology is directed to both basic and clinical scientists working in membrane transport and related areas, to graduate students and advanced undergraduates seeking a broad purview of the subject, and to other investigators and potential investigators seeking a vista of the new frontiers of molecular epithelial transporters.
Mechanisms ofwater flow across epithelial membranecomponents Osmosis Electro-osmosis Summary References INTRODUCTION Water and solutes are transported by many epithelia from one side of the cell Transport mechanisms in epithelia book to another. In certain epithelia, Cited by: Membrane Transport across Polarized Epithelia.
Proteins and peptides required for brain homeostasis cross the blood–brain barrier via transcellular transport, but the mechanisms that control. After the pioneering studies by Ussing and co-workers, studies of epithelial Nael transport have come a long way. The first phase of the phenomenological description of the cell as a black box has been follow ed by studies of cellular mechanisms, the interplay of the different trans port components, and the mechanisms of regulation.
11 Transport across epithelia. Epithelial tissues form a protective barrier around the body, both outside and inside. On the outside they mostly lock internal milieu from the environmental influence, making our skin and mucosal membranes totally impermeable and waterproof.
However, on the inside, epithelial cells develop to be semipermeable dividers specialized for regulated environmental. The greater inhibition of Na + transport by serosal ouabain compared to the inhibition when ouabain was added to the mucosal side (Keynes and Harrison ) indicates that the basolateral exit of Na + depends—as in other epithelia—on the Na + /K +-ATPase, and that the apical entry of Na + occurs owing to secondary active by: Epithelial transport of sugars and amino acids (X).
In the G.I. tract and kidney, solutes are pumped into cells via a secondary active transporter, driven by the inward sodium leak. The solutes diffuse across the cell, and are transported down their energy gradient out of the cell across the basolateral membrane by way of facilitated diffusion.
Transporters in Vertebrate Small Intestine -- The H+- and H+, K+-ATPases of the Collecting Duct -- Acid\/Base Regulation in Renal Epithelia by H, K-ATPases -- Sodium Transport Mechanisms in the Mammalian Nephron -- Renal Acid-Base Regulation Via Ammonia Transport in Mammals -- Hexose Transport Across Mammalian Epithelia -- Amino Acid Transport.
The mechanism of fluid transport by leaky epithelia and the route taken by the transported fluid are in dispute. A consideration of current mathematical models for coupling of solutes and water, as well as the methodologies for the study of fluid transport, shows that local osmosis best accounts for water movement.
Although it seems virtually certain that the tight junctions are water Cited by: Buy Folate Transport & DNA Methylation:The Molecular Approach: Mechanisms of Folate Transport in Absorptive Epithelia and Impact on Cellular DNA Methylation on.
This book is also an attempt to analyze the molecular basis for the movement of various solutes across an epithelial cell membrane. This volume is devoted to a diversity of epithelial transport mechanisms in rep- sentative cell membranes of a variety of living : Humana Press.
Transcellular Transport. Transcellular transport is the pathway of substances through the intestinal epithelial cells by transcytosis, a process by which particles are taken up by cells, depending on various physicochemical properties of particles, such as lipophilicity, size, hydrogen bond potential, surface hydrophobicity, charge, the physiology of the GI tract, and the presence of a ligand.
After the pioneering studies by Ussing and co-workers, studies of epithelial Nael transport have come a long way.
The first phase of the phenomenological description of the cell as a black box has been follow- ed by studies of cellular mechanisms, the interplay of the different trans- port components, and the mechanisms of regulation. Transport across Epithelia: The probably best example to comprehend the basic mechanisms of transepithelial transport is the amphibian skin as it was first described by Hans H.
Ussing and his coworkers in the 50ies of the last century. Indeed, it is known today that certain features of this tissue are more complicated as had been believed. - vital concept in transport epithelia - epithelia have two distinct sides that carry out distinct functions: the apical (or luminal) side facing the lumen of the organ and the basolateral (or interstitial) side facing the intercellular solution and the bloodstream.
This book is also an attempt to analyze the molecular basis for the movement of various solutes across an epithelial cell membrane. This volume is devoted to a diversity of epithelial transport mechanisms in rep- sentative cell membranes of a variety of living things. Ion transport accomplished by the pulmonary epithelial cells is imperative for proper lung function.
Although the basic mechanisms of transepithelial ion transport are defined, it is obvious that a detailed knowledge concerning the underlying processes and the interaction of the different ion transporting proteins in particular is poorly Cited by: Molecular Mechanisms of Water Transport (Molecular Biology Intelligence Unit) Hardcover – February 1, by Thomas Zeuthen (Author) › Visit Amazon's Thomas Zeuthen Page.
Find all the books, read about the author, and more. See search results for this author. Are you an author? Cited by: Active transport mechanisms do just this, expending energy (often in the form of ATP) to maintain the right concentrations of ions and molecules in living cells 11/14/16 11 2 Types of Active Transport Mechanism • Primary Active Transport – these are found in all living organisms and require an energy source such as ATP for the.